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Heartworm disease


Heartworm Disease

Heartworm disease
Heartworm is a serious and potentially fatal disease in dogs. It is caused by a worm called Dirofilaria immitis, of which the adult lives in the heart and pulmonary arteries. The female worm is 2.3 to 5.5 cm long and 5 mm wide; the male is about half the size of the female. One dog may have as little as 1 or as many as 300 adult worms.




Lifecycle
The average life span is up to 5 years and, during this time, the female produces millions of young (microfilaria). These microfilaria live in the bloodstream, mainly in the small blood vessels near the skin. The immature heartworms cannot complete their life cycle in the dog; a mosquito is required for some stages of the heartworm life cycle. The disease is not spread directly from dog to dog. The mosquito, is required for transmission As many as 30 species of mosquitoes can transmit heartworms. The female mosquito bites the infected dog and ingests the microfilaria during a blood meal. The microfilaria develop further for 10 to 30 days in the mosquito and then enter the mouth parts of the mosquito. The microfilaria are now called infective larvae because at this stage of development, they will grow to adulthood when they enter a dog. The mosquito bites the dog where the hair coat is thinnest. Having long hair obviously does not prevent a dog from getting heartworms. (The mosquito will just bite the dog on the thinly haired areas, nose, inner thigh and bellie) When fully developed, the infective larvae enter the bloodstream and move to the heart and adjacent vessels, where they grow to maturity in 2 to 3 months and start reproducing, thereby completing the full life cycle.



Symptoms
It takes a number of years before dogs show outward signs of infection. Consequently, the disease is diagnosed mostly in 4 to 8 year old dogs. Heartworm cause disease by clogging the heart and the major blood vessels of the heart. They interfere with the valve action in the heart causing heart disease and by clogging the main blood vessels, the blood supply to other organs of the body is reduced, particularly the lungs, liver and kidneys, leading to malfunction of these organs. The signs of heartworm disease depend on the number of adult worms present, the location of the worms, the length of time the worms have been present, and the degree of damage to the heart, lungs, liver, and kidneys from the adult worms.  The most obvious signs are: a soft, dry, chronic cough, shortness of breath, weakness, nervousness, listlessness, and loss of stamina. All of these signs are most noticeable following exercise, when some dogs may even collapse.Severely infected dogs may die suddenly during exercise or excitement.
Listening to the chest with a stethoscope will often reveal abnormal lung and heart sounds. In advanced cases, congestive heart failure may be apparent and the abdomen and legs will swell from fluid accumulation. There may also be evidence of weight loss, poor condition, and anaemia.

Diagnoses
In order to diagnose the presence of heartworm we may need to carry out some tests. Blood tests for adult antigen or microfilaria, Blood chemistries: routine blood test to examine the function of abdominal organs and radiographs and ultrasonography: to examine the changes to the heart and major vessels if heartworm is present.

Treatment
Treatment of heartworm is complicated and has risks involved with it, if your dog is diagnosed with heartworm infection we will discuss the treatment and risks involved. The treatment can last 1-2 months, and even then may not be effective. If there is permanent damage to the heart or abdominal organs this will still be present even after eradication of the infection.

Prevention
Prevention is in this case far better than cure. Prevention involves killing the microfilaria before they develop in to adults. This can be done in a number of ways.
  • Daily treatment is not used much these days as there are safer and more effective preventions available.
  • Monthly treatment which are given orally or topically. They will kill the microfilaria (infective larvae) in the dog before they reach maturity. If the is a gap of 2-3 months there is a chance that larvae may have matured into adults and will not be killed by the monthly treatment.
  • Yearly treatment -Dogs may also be given a yearly Proheart injection to kill any infective larvae. The Proheart injection is given from 3 months of age. When given at 3 months of age it will remain at effective levels for 6 months NOT a year ( this is because the dog is still growing and will not weight the same at 9 months of age as 3 months of age) if given from 9 months of age the levels will be effective for a full 12 months.